Karyopharm Therapeutics is a commercial-stage pharmaceutical company whose dedication to pioneering novel cancer therapies is fueled by a belief in the extraordinary strength and courage of patients with cancer. Since its inception in 2008, the company has been at the forefront of developing pioneering SINE technology to disrupt nuclear protein export in cancer cells. With over a decade of research, Karyopharm has one FDA-approved product available across the US, EU, UK, and Israel, and four drug candidates in clinical trials. The team’s rich experience in cancer therapy development and commercialization underpins its mission to accelerate novel therapeutics for life-threatening diseases. Emphasizing a culture of innovation and integrity, Karyopharm is dedicated to improving patient outcomes through scientific excellence.
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Karyopharm’s vision of boundless opportunity is rooted in defeating cancer, with employees at every level contributing to this mission. From the commercial team to scientists and financial officers, each role is seen as essential. This shared goal of advancing three, phase-three clinical trials and expanding into new indications fosters a united, optimistic outlook.
The ICARE values at Karyopharm resonate with employees by emphasizing innovation, courage, alignment and accountability, resilience, and energy. Through quarterly ICARE awards, employees who embody these values are recognized and celebrated, ensuring values alignment is promoted and upheld.
Karyopharm’s CEO exemplifies the company values in many ways. Most recently, he advocated for the KaryoFlex program, which allows flexible work hours, supporting work-life balance. He also established Core Weeks for in-person collaboration, showcasing a commitment to innovation and adaptability in the workplace.
Respect and inclusivity are ingrained all we do. Some ways Karyopharm demonstrates this is through regular feedback, diversity partnerships, and KaryoBites sessions that disseminate cross-functional knowledge and achievements. Diverse global teams are celebrated through various initiatives, such as employee resource groups, ensuring all voices are heard and valued.
Employees at Karyopharm engage in collaboration through a dynamic, fast-paced culture where every contribution is vital. This enables organic connections across departments, crucial for quick decision-making and course corrections. Our company’s size supports this close-knit interaction, uniting employees as they advance their core programs.
Candidates highlight Karyopharm’s competitive compensation and benefits package as a reason they join the company. On top of this, KPTI offers an industry-leading flexible working model, including KaryoFlex Fridays, where we allow employees to decide how to best balance the needs of the business and their personal needs. Karyopharm also provides an annual $1200 stipend for employees to use toward wellness and other self-care practices to promote a culture where it’s encouraged to take care of yourself.